Platform pioneering “digital residency” for clinical AI reaches 3M+ autonomous patient encounters with 100% safety pass rate

NEW YORK–(BUSINESS WIRE)–Amigo AI, the platform for building and training patient-facing clinical agents, today announced an $11M Series A led by Madrona with participation from Optum Ventures. The company has now raised $17M in total funding, including a seed round co-led by General Catalyst and GSV Ventures. The raise comes amid growing momentum for the application of AI in healthcare, fueled by regulatory shifts toward technology-enabled care delivery (e.g., CMS ACCESS model) and growing provider demand for clinical agents.

Amigo builds and trains AI agents that interact directly with patients across clinical use cases such as intake and triage, personalized care navigation, and 24/7 patient support. By handling high-value clinical workflows, Amigo agents enable healthcare organizations to improve patient outcomes and meaningfully expand the reach and impact of their existing care teams.

In just the last six months, Amigo agents have completed over three million patient encounters around the world with zero safety incidents. The company now powers clinical AI for leading healthcare organizations around the world, including Eucalyptus, Diverge Health, and The Care Clinic.

“Amigo is addressing one of the hardest problems in healthcare AI, deploying autonomous systems where trust and safety are non-negotiable,” said Sabrina Albert, Partner at Madrona. “Their simulation-first approach to clinical safety positions them to define the standard for patient-facing AI.”

By 2030, the world will face a shortage of 11 million health workers. Clinical agents offer a promising path to closing this gap, but only if they can deliver care as safely as human clinicians.

“We train our agents like doctors because mistakes can cost lives in healthcare,” said Ali Khokhar, Founder and CEO of Amigo. “No agent should interact with a real patient until it’s been rigorously trained and proven safe.”

Amigo’s safety-first approach to clinical AI is made possible by three key innovations:

• An agent brain modeled on how doctors think. Amigo agents are built using proprietary AI architecture that mirrors the cognitive process of a clinician, from recalling a patient’s full history to knowing when a case requires escalation.
• A digital residency modeled on how doctors are trained. Every Amigo agent trains across millions of simulated scenarios modeled on each practice’s unique patient population before ever seeing a real patient. Simulations deliberately overindex on adversarial patients and edge cases, and agents continue to learn and improve across dimensions like accuracy, empathy, and harm prevention until they reach a 100% safety pass rate.
• A connected platform where multiple agents work together like a care team. Amigo agents share unified patient context in real time, eliminating information loss to facilitate safe handoffs and clinical actions. This enables healthcare organizations to automate complex team-based workflows on a single platform rather than implementing point solutions that require ongoing provider oversight.

Beyond the platform, Amigo is strengthening its clinical and strategic leadership. The company recently appointed Dr. Jay Shah, Chief of the Medical Staff at Stanford Health Care, as Chief Medical Advisor.

“In my 23 years of practicing medicine, I’ve watched the demand for care outpace our ability to deliver it,” said Dr. Jay Shah. “Amigo’s approach of training agents with the same rigor we expect of clinicians means they can operate at the standard I’ve seen at Stanford, Columbia, and MD Anderson.”

About Amigo

Amigo is transforming care delivery with the industry’s first approach to training AI agents like doctors. The company partners with healthcare organizations to define their AI strategy and build custom agents that launch safely at scale in over 100 languages. Enterprise deployment is supported by native integrations into all major EHRs (Epic, Oracle Health, Athenahealth, and more) and full HIPAA, SOC 2 Type II, and GDPR compliance. For more information, visit www.amigo.ai.

Contacts

Richard Wang (Head of GTM)
info@amigo.ai

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