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Nucleus RadioPharma Secures Series A Extension Funding with AstraZeneca Investment

Nucleus RadioPharma Secures Series A Extension Funding with AstraZeneca Investment

June 5, 2024 Craig Etkin

Dr. Tyrell Rivers joins the Nucleus Board of Directors

June 05, 2024 05:00 AM Pacific Daylight Time

ROCHESTER, Minn.–(BUSINESS WIRE)–Nucleus RadioPharma, the world’s first fully integrated development, manufacturing, and supply chain organization for radiopharmaceuticals, today announced the closing of a Series A extension round with new investor AstraZeneca (LSE/STO/Nasdaq: AZN). AstraZeneca joins existing investors from GE Healthcare, Mayo Clinic, Eclipse Ventures, Fox Chase Cancer Center, Echo Global Granger Management Mercy Health, and the University of Missouri as Nucleus expands development, supply, and commercial manufacturing capabilities to make targeted radiotherapies and theranostics more accessible to patients globally. Concurrent with the financing, Tyrell Rivers, PhD, Executive Director of Corporate Ventures at AstraZeneca, was named to the Board of Directors.

“These drugs, designed for precise targeting, are demonstrating remarkable effectiveness while upholding an exceptional safety record. The funding expands the accessibility and impact of these life-saving treatments, paving the way for large-scale production and instilling optimism in those with limited options.”

Theranostics combines diagnostics and therapeutics for personalized cancer treatment using radiotracers that selectively bind to specific cancer cells. A low-dose radiotracer helps visualize tumors, guiding targeted therapy, while a higher-dose radiotracer delivers potent radiation to kill cancer cells with minimal damage to healthy tissues. This precision approach reduces side effects compared to traditional treatments and shows promise in treating metastatic cancers like neuroendocrine tumors, prostate cancer, and lymphoma.

“Theranostic radiopharmaceuticals represent a new hope for millions of people with limited treatment alternatives,” said Nucleus RadioPharma CEO Charles S. Conroy. “These drugs, designed for precise targeting, are demonstrating remarkable effectiveness while upholding an exceptional safety record. The funding expands the accessibility and impact of these life-saving treatments, paving the way for large-scale production and instilling optimism in those with limited options.”

Dr. Tyrell Rivers is Executive Director of Corporate Ventures at AstraZeneca, where he is responsible for creating and executing innovative, value-enhancing business strategies. Prior to assuming this role in 2014, he worked at MedImmune Ventures, specializing in life science investing. Earlier in his career, Dr. Rivers held various positions at Merck & Co., where he led technical support for commercial vaccines and directed global business initiatives for accessing key technologies for research and development. He is a Board member of ADC Therapeutics, Cellectis, Cerapedics, and Quell Therapeutics. Dr. Rivers holds his B.S. in Chemical Engineering from the Massachusetts Institute of Technology, a Ph.D. in Chemical Engineering from the University of Texas at Austin, and an M.B.A. from the New York University Stern School of Business.

With more than 20 years of supporting business initiatives in the investment and life science sectors, Dr. Rivers brings extensive experience in aiding company growth, directing corporate strategy, and establishing financially sound businesses.

Conroy added: “The support of AstraZeneca and Tyrell on the board has ignited our excitement as this funding will facilitate the expansion of our development, supply, and commercial manufacturing capabilities, ultimately enhancing global accessibility to targeted radiotherapies and theranostics for patients worldwide.”

Radiopharmaceuticals offer precise cancer treatment, but the intricate supply chain, akin to managing a rapidly melting ice cube, demands precise timing due to the perishable nature of radioactive materials, consequently restricting patient access. Nucleus RadioPharma is at the forefront of addressing these challenges by enhancing manufacturing and supply chain efficiency, to broaden the accessibility of radiopharmaceuticals as a promising frontier in oncology.

About Nucleus RadioPharma

Nucleus RadioPharma is an innovative CDMO in the radiopharmaceutical industry, dedicated to the development and manufacturing of targeted radiotherapies. With an emphasis on innovation and quality, the company provides an array of services, from formulation and analytical development to regulatory documentation and drug product manufacturing. Nucleus RadioPharma’s technology platforms are at the forefront of radiopharmaceutical research, designed to advance new therapies through clinical trials to commercialization. Recognized for its flexible approach, the company offers multiple onboarding points to accommodate innovators at various stages of their product lifecycle. Backed by Eclipse, GE HealthCare, Echo Global, Fox Chase Cancer Center, Granger Management, Mayo Clinic, Mercy Health, and University of Missouri, Nucleus RadioPharma stands well-supported by leading institutions and organizations committed to advancing healthcare through innovative solutions. Please visit nucleusrad.com and follow us on LinkedIn for more information.

Contacts

Patrick Schmidt
630-290-2787
nucleusrad@consortpartners.com

(c)2024 Business Wire, Inc., All rights reserved.


Venture Capital
Business Wire, Minnesota, Nucleus RadioPharma, Rochester, Venture Capital

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Joby Aviation, a company developing electric air taxis for commercial passenger service, announced the successful closing of the first $250 million tranche of a previously announced strategic investment from Toyota Motor Corporation. The funding marks a significant milestone in strengthening the long-term collaboration between the two companies and supports their shared vision for the future of air mobility. The investment is aimed at supporting certification and commercial production of Joby’s electric air taxi. This underscores the mutual commitment to deepening integration and delivering next generation travel to global markets. This investment also puts the two companies a step closer toward a strategic manufacturing alliance.

In a statement JoeBen Bevirt, founder and CEO of Joby said, “We’re already seeing the benefit of working with Toyota in streamlining manufacturing processes and optimizing design.” “This is an important next step in our alliance with Toyota to scale the promise of electric flight. With this capital and Toyota’s legendary production expertise, we’re enhancing our ability to scale cutting-edge design and manufacturing to meet the demands of our partners and customers.”

Joby Aviation is a California-based transportation company developing an all-electric, vertical take-off and landing air taxi which it intends to operate as part of a fast, quiet, and convenient service in cities around the world. Powered by six electric motors, their aircraft takes off and lands vertically, giving it the flexibility to serve almost any community. Flying with Joby might feel more like getting into an SUV than boarding a plane. The company's aerial ridesharing service will combine the ease of conventional ridesharing with the power of flight. A green alternative to driving that's bookable at the touch of an app. With more than 30,000 miles flown on full-scale prototype aircraft, their aircraft is designed to meet the uncompromising safety standards set by the FAA and other global aviation regulators. Joby Aviation is now engaged in a multi-year testing program with the FAA to certify their vehicle for commercial operations, and have completed the first three of five stages.
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Infinite Reality, an innovation company powering the next generation of immersive media, AI, and ecommerce, today announced a landmark real estate partnership with renowned real estate investment, development and management firm Sterling Bay to co-develop a 60-acre site in Fort Lauderdale into a next-generation technology and entertainment campus. This ambitious redevelopment—expected to open in 2026—will serve as Infinite Reality’s new global headquarters and is the cornerstone of iR’s long-term real estate strategy, which begins with this flagship project in South Florida. The public-private project marks one of the largest creative economy investments in the area to date, aiming to generate more than 1,000 new jobs with an average salary of six figures and deliver long-term economic growth to the region. Located at 1400 NW 31st Avenue on the site of a remediated former Superfund property, the development features over 100,000 square feet of Class A office space for media, tech, and enterprise clients. Construction is expected to begin in early 2026, pending completion of permitting and design phases.

In a statement John Acunto, co-founder and CEO of Infinite Reality said, “This isn’t just a headquarters—it’s the heart of Infinite Reality’s future. As a proud South Florida resident, this project is deeply personal to me.” “It’s about transforming a community I love into a global hub for immersive technology and creativity. We’re building opportunity, fueling innovation, and laying the foundation for a lasting legacy. Partnering with a world-class development firm like Sterling Bay ensures that this vision is realized at the highest level—and that Fort Lauderdale becomes a defining force in the future of the digital economy.”

In addition to serving as a corporate campus, the site will include flexible spaces for retail, production, digital broadcasting, and entertainment ventures. The development also includes educational initiatives in partnership with local institutions to train and hire future talent in STEM, immersive tech, and creative production. Infinite Reality is an innovation company powering the next generation of digital media and ecommerce through spatial computing, artificial intelligence, and other immersive technologies. Infinite Reality’s suite of cutting-edge software, production, marketing services, and other capabilities empower brands and creators to craft inventive digital experiences that uplevel audience engagement, data ownership, monetization, and brand health metrics.
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Kimberly-Clark Corporation, one of the world's leading manufacturers of personal care and hygiene products, will establish an $800 million advanced manufacturing facility in Trumbull County, bringing an anticipated 491 new high-quality jobs. For Kimberly-Clark, this new facility would be its first in Ohio and represents not just a strategic expansion, but a decisive step in doubling down on growth in the American market. Spread across more than one million square feet, the Warren facility will provide the manufacturing capacity needed to unleash future growth for Kimberly-Clark’s fastest-growing personal care categories that include Baby & Child Care and Adult & Feminine Care. Warren is in geographic proximity to roughly 117 million consumers and will serve as a strategic hub for the Northeast and Midwest regions. Construction is expected to begin this month and will take up to two years.

In a statement Tamera Fenske, chief supply chain officer at Kimberly-Clark said, “Our investment in Warren is a pivotal step forward in our North America business and strategy.” “By establishing a new, state-of-the-art manufacturing facility in Ohio, we’re enhancing our ability to serve millions of consumers across the Midwest and Northeast with greater speed, agility, and resilience. It’s a once-in-a-career opportunity to build a facility from the ground up that reflects the future of manufacturing, and with the support of local partners like JobsOhio, the Department of Development, Lake to River, Western Reserve Port Authority, and local governments, we have the unique opportunity to create high-quality jobs and long-term economic impact in the region.”

Based in Dallas and employing 46,000 people in 34 countries, the company’s portfolio of brands also includes Huggies, Kleenex, Scott, Kotex, Cottonelle, Poise, Depend, Andrex, Pull-Ups, GoodNites, Intimus, Plenitud, Sweety, Softex, Viva and WypAll. Its products are sold in more than 175 countries and territories.
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