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Aether Biomachines Raises $15M to Reindustrialize America with AI-Designed Proteins

Aether Biomachines Raises $15M to Reindustrialize America with AI-Designed Proteins

December 16, 2025 Craig Etkin
  • Backed by Tribe Capital, Natural Capital, Henkel Corporation, and more, Aether Bio leverages AI to design working proteins for materials, critical mineral extraction, CO2 removal, and forever-chemical cleanup.
  • To date, Aether’s AI-designed proteins have helped create super materials up to 10X faster and 2X stronger, critical for national security, manufacturing, aerospace, defense, sustainability, and more.

SAN FRANCISCO–(BUSINESS WIRE)–Aether Biomachines, the company reindustrializing America by turning AI-designed proteins into real-world solutions, today announced an additional $15 million in funding led by Tribe Capital, with participation from new and existing investors including Natural Capital, Henkel Corporation, Resilience Reserve, Shrug Capital, 4DX Ventures, Unless Partners, and Radicle Impact. The round brings Aether’s total funding to $64 million.

It’s been decades since the last industrial revolution, with only incremental improvements to chemical manufacturing being made since then due to the billions of dollars it takes to build factories on outdated chemical processes. Aether has a different approach – combining purpose-built AI and high-throughput robotics to design proteins that act like molecular assemblers, tiny machines that build, one atom at a time. These nanoscale machines have the precision and sophistication of massive chemical factories, but at a fraction of the size, enabling Aether to make new products faster, more affordably, and more sustainably.

Aether will use its latest funding to expand its Protein Function Model to rapidly design and optimize proteins for industrial and environmental applications, scale its first commercial materials products, and accelerate partnerships with companies looking to apply its AI-powered proteins across manufacturing, sustainability, and national security.

“Aether is building the foundation for the next industrial revolution,” said Pavle Jeremić, CEO and Founder of Aether Biomachines. “This funding will allow us to accelerate the discovery of proteins with transformative applications, including stronger, more scalable materials for defense and aerospace, and bring our first commercial products to more industries. Our latest funding positions us to turn breakthrough science into real-world solutions.”

Aether’s AI-designed proteins are already delivering transformative results across materials and industrial applications, including:

  • Super materials: newpolymer additives RapidPrint and Ultra 3D print up to 10X faster and 2X stronger than industry benchmarks, powering drones for defense and complex parts for the aerospace industry.
  • Industrial solutions: seven new classes of proteins capable of extracting rare earth metals, recycling plastics, capturing carbon, breaking down “forever chemicals”, and producing complex pharmaceuticals.

These breakthroughs demonstrate the broad potential of AI-designed proteins to transform industries and reduce reliance on global supply chains.

“We’ve seen many AI companies focus on discovery, but no one has taken the leap from designing proteins to delivering physical, market-ready products until Aether,” said Arjun Sethi, Chairman at Tribe Capital. “Aether is proving that its approach isn’t just innovative in theory; it’s faster, more cost-effective, and higher-performing than traditional methods, setting the standard for what AI-driven chemistry can achieve in the real world.”

To learn more about Aether, visit: https://www.aetherbio.com

About Aether Biomachines

Aether Biomachines is an American artificial intelligence company that discovers proteins with high-impact, real-world applications. At the core of its work is a Protein Function Model that can unlock new proteins for novel functions. Aether’s AI is being built on an entirely proprietary dataset developed in-house through advanced high-throughput screening and innovative assay technology. Using this platform, Aether has developed seven new classes of proteins with capabilities ranging from refining metals at lower cost and breaking down persistent “forever chemicals” to producing industry-leading materials, enabling complex pharmaceutical manufacturing, recycling plastics, and capturing carbon dioxide. Aether is already translating its AI breakthroughs into practice, commercializing high-performance materials that can print ten times faster than current industry benchmarks while offering superior strength for the defense and aerospace industries. Learn more at https://www.aetherbio.com/.

Contacts

Media Contact
Michelle Mead
VSC for Aether Biomachines
aetherbio@vsc.co

(c)2025 Business Wire, Inc., All rights reserved.


Venture Capital
Aether Biomachines, Business Wire, California, San Francisco, Venture Capital

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Fabric, a leader in care delivery and consumer experience, has announced the acquisition of UCM Digital Health (UCM), a leading digital health and telehealth provider. The acquisition expands Fabric's services to about 400 new employer and payer customers, adding one million covered lives. Fabric now serves over 75 health systems, 30,000 employers, and over 100 million lives across all 50 states. This marks Fabric’s fifth acquisition in less than three years, underscoring its strategic build-and-buy approach to unify the fragmented digital health landscape. By expanding its footprint in the payer and employer markets, Fabric is extending its comprehensive care access and experience platform paired with its nationwide provider network to streamline virtual-first care, expand access, improve efficiency and outcomes, and reduce both medical and overhead costs.

In a statement Aniq Rahman, CEO and Founder of Fabric said, "For Fabric, it’s about making healthcare more accessible.” “We’ve already made meaningful progress in the payer and employer markets, and this acquisition allows us to deepen that impact. By bringing more payers and employers onto our platform, we’re creating a connected experience that streamlines workflows, reduces friction and costs, and ultimately drives better outcomes for members and our partners." Moving forward, the 400 payers and employers served by UCM will transition to Fabric’s expanded technology and clinical network, gaining access to enhanced omnichannel patient experiences that improve efficiency before, during, and after virtual care. Through Fabric’s nationwide provider network, patients can receive a treatment plan for most common medical conditions in just five minutes or connect with a behavioral health provider within three days.

Fabric is a health tech company on a mission to solve healthcare’s access problem. Fabric’s integrated care platform offers personalized guidance, streamlines workflows, and unifies experiences across virtual and in-person care. Its solutions support care delivery from a patient’s first search to post-treatment follow-up using its proprietary Hybrid AI that combines conversational AI and physician-built clinical logic. Together with a nationwide network of medical and behavioral health providers, Fabric is realizing its vision of providing care for everyone, everywhere. The company advances connected delivery that improves access, outcomes, and equity across every stage of the patient journey. Today, Fabric serves 30,000 employers, payers, and enterprise organizations, including OSF HealthCare, MUSC Health, Highmark, and Intermountain Health. Fabric is backed by General Catalyst, Thrive Capital, GV (Google Ventures), Salesforce Ventures, Vast Ventures, BoxGroup, and Atento Capital.
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Flex has closed a $60 million Series B equity round led by Portage, bringing total equity raised to $105 million. In the last year, the company has quadrupled revenue and tripled its payments volume to $3 billion as it scales its all-in-one business and personal finance platform for high-net-worth middle-market business owners. Running a profitable middle-market business has become one of the most complex financial jobs in America, with owners often juggling more than ten disconnected systems to manage their money. Flex was created to give these high net worth owners a single place to run both their business and personal finances. This latest $60 Million equity round, followed by its $200 Million debt and $25 Million equity raise announced earlier this year, builds on a period of rapid hypergrowth. In just 12 months, Flex has grown revenue fourfold and increased annualized total payments volume from $1 billion to $3 billion across a suite of products, positioning Flex as one of the fastest-growing fintech companies at scale with best-in-class capital efficiency.

Flex is building the category-defining company solving this gap for high net worth business owners with a five-pillar strategy built around private credit, a business finance stack, a personal finance stack, payment solutions, and an ERP built for middle market businesses. These customers now use an average of four or more Flex products. Flex’s Business Credit Card, which provides 60-day float on every transaction, has been a major driver of adoption, acting as the wedge into deeper financial operations. Once owners experience the benefits of the Flex Credit Card, they often go on to adopt Flex’s banking, payments, working capital, and expense management tools to replace fragmented legacy systems. This integrated model has allowed Flex to scale with high efficiency and has created a strong foundation for its expansion into personal finance.

Launched in 2023, Flex a Flexbase Technologies brand is the AI Native “Private Bank” for high net worth business owners in the middle market. Flex is building the category-defining company solving this gap for high net worth business owners with a five-pillar strategy built around private credit, a business finance stack, a personal finance stack, payment solutions, and an ERP built for middle market businesses. Flex is the first platform that supports every step of their financial lives, from the moment they earn revenue to the moment they spend it personally.
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Across the United States, a new industrial age is taking shape. Trillions of dollars in infrastructure, from energy projects and advanced manufacturing to data centers and critical mineral facilities, must be built in the next decade. But large construction projects are slower and more expensive today than they were half a century ago. Unlimited Industries, a California-based company using AI to rethink how infrastructure gets built, has raised $12 million in seed funding to change that. The round was co-led by Andreessen Horowitz and CIV, with participation from leading industry investors. The capital will accelerate Unlimited’s expansion and further develop its proprietary AI platform – one designed to make large-scale engineering and construction faster, cheaper, and more ambitious.

Unlike traditional construction firms or standard software companies, Unlimited is an AI-native construction company that both designs and builds. Its proprietary platform can generate and evaluate hundreds of thousands of design configurations in parallel, automatically identifying optimal layouts for cost, safety, and performance before construction begins. By integrating AI-driven design with its own vertically integrated engineering and construction teams, Unlimited eliminates the costly handoffs and misaligned incentives that have defined the industry for decades.

In a statement Alex Modon, Co-Founder and CEO of Unlimited Industries said, “Advances in AI mean we can finally build the physical world the way we build software.” “The traditional construction model is slow, brittle, and fundamentally misaligned. Our approach replaces static design choices with a dynamic, data-driven process that learns from every project. The result is faster, cheaper, and more successful projects.”

Unlimited is an AI-native construction company headquartered in San Francisco. Today, the company designs and builds across energy infrastructure, data centers, critical minerals, and advanced manufacturing, helping developers build with greater speed, ambition, and efficiency. Their mission is to build a future of radical physical abundance by automating construction end-to-end. The company was founded in 2025 by serial founders Alex Modon, Jordan Stern, and Tara Viswanathan.
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