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Nucleus RadioPharma Secures Series A Extension Funding with AstraZeneca Investment

Nucleus RadioPharma Secures Series A Extension Funding with AstraZeneca Investment

June 5, 2024 Craig Etkin

Dr. Tyrell Rivers joins the Nucleus Board of Directors

June 05, 2024 05:00 AM Pacific Daylight Time

ROCHESTER, Minn.–(BUSINESS WIRE)–Nucleus RadioPharma, the world’s first fully integrated development, manufacturing, and supply chain organization for radiopharmaceuticals, today announced the closing of a Series A extension round with new investor AstraZeneca (LSE/STO/Nasdaq: AZN). AstraZeneca joins existing investors from GE Healthcare, Mayo Clinic, Eclipse Ventures, Fox Chase Cancer Center, Echo Global Granger Management Mercy Health, and the University of Missouri as Nucleus expands development, supply, and commercial manufacturing capabilities to make targeted radiotherapies and theranostics more accessible to patients globally. Concurrent with the financing, Tyrell Rivers, PhD, Executive Director of Corporate Ventures at AstraZeneca, was named to the Board of Directors.

“These drugs, designed for precise targeting, are demonstrating remarkable effectiveness while upholding an exceptional safety record. The funding expands the accessibility and impact of these life-saving treatments, paving the way for large-scale production and instilling optimism in those with limited options.”

Theranostics combines diagnostics and therapeutics for personalized cancer treatment using radiotracers that selectively bind to specific cancer cells. A low-dose radiotracer helps visualize tumors, guiding targeted therapy, while a higher-dose radiotracer delivers potent radiation to kill cancer cells with minimal damage to healthy tissues. This precision approach reduces side effects compared to traditional treatments and shows promise in treating metastatic cancers like neuroendocrine tumors, prostate cancer, and lymphoma.

“Theranostic radiopharmaceuticals represent a new hope for millions of people with limited treatment alternatives,” said Nucleus RadioPharma CEO Charles S. Conroy. “These drugs, designed for precise targeting, are demonstrating remarkable effectiveness while upholding an exceptional safety record. The funding expands the accessibility and impact of these life-saving treatments, paving the way for large-scale production and instilling optimism in those with limited options.”

Dr. Tyrell Rivers is Executive Director of Corporate Ventures at AstraZeneca, where he is responsible for creating and executing innovative, value-enhancing business strategies. Prior to assuming this role in 2014, he worked at MedImmune Ventures, specializing in life science investing. Earlier in his career, Dr. Rivers held various positions at Merck & Co., where he led technical support for commercial vaccines and directed global business initiatives for accessing key technologies for research and development. He is a Board member of ADC Therapeutics, Cellectis, Cerapedics, and Quell Therapeutics. Dr. Rivers holds his B.S. in Chemical Engineering from the Massachusetts Institute of Technology, a Ph.D. in Chemical Engineering from the University of Texas at Austin, and an M.B.A. from the New York University Stern School of Business.

With more than 20 years of supporting business initiatives in the investment and life science sectors, Dr. Rivers brings extensive experience in aiding company growth, directing corporate strategy, and establishing financially sound businesses.

Conroy added: “The support of AstraZeneca and Tyrell on the board has ignited our excitement as this funding will facilitate the expansion of our development, supply, and commercial manufacturing capabilities, ultimately enhancing global accessibility to targeted radiotherapies and theranostics for patients worldwide.”

Radiopharmaceuticals offer precise cancer treatment, but the intricate supply chain, akin to managing a rapidly melting ice cube, demands precise timing due to the perishable nature of radioactive materials, consequently restricting patient access. Nucleus RadioPharma is at the forefront of addressing these challenges by enhancing manufacturing and supply chain efficiency, to broaden the accessibility of radiopharmaceuticals as a promising frontier in oncology.

About Nucleus RadioPharma

Nucleus RadioPharma is an innovative CDMO in the radiopharmaceutical industry, dedicated to the development and manufacturing of targeted radiotherapies. With an emphasis on innovation and quality, the company provides an array of services, from formulation and analytical development to regulatory documentation and drug product manufacturing. Nucleus RadioPharma’s technology platforms are at the forefront of radiopharmaceutical research, designed to advance new therapies through clinical trials to commercialization. Recognized for its flexible approach, the company offers multiple onboarding points to accommodate innovators at various stages of their product lifecycle. Backed by Eclipse, GE HealthCare, Echo Global, Fox Chase Cancer Center, Granger Management, Mayo Clinic, Mercy Health, and University of Missouri, Nucleus RadioPharma stands well-supported by leading institutions and organizations committed to advancing healthcare through innovative solutions. Please visit nucleusrad.com and follow us on LinkedIn for more information.

Contacts

Patrick Schmidt
630-290-2787
nucleusrad@consortpartners.com

(c)2024 Business Wire, Inc., All rights reserved.


Venture Capital
Business Wire, Minnesota, Nucleus RadioPharma, Rochester, Venture Capital

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Fabric, a leader in care delivery and consumer experience, has announced the acquisition of UCM Digital Health (UCM), a leading digital health and telehealth provider. The acquisition expands Fabric's services to about 400 new employer and payer customers, adding one million covered lives. Fabric now serves over 75 health systems, 30,000 employers, and over 100 million lives across all 50 states. This marks Fabric’s fifth acquisition in less than three years, underscoring its strategic build-and-buy approach to unify the fragmented digital health landscape. By expanding its footprint in the payer and employer markets, Fabric is extending its comprehensive care access and experience platform paired with its nationwide provider network to streamline virtual-first care, expand access, improve efficiency and outcomes, and reduce both medical and overhead costs.

In a statement Aniq Rahman, CEO and Founder of Fabric said, "For Fabric, it’s about making healthcare more accessible.” “We’ve already made meaningful progress in the payer and employer markets, and this acquisition allows us to deepen that impact. By bringing more payers and employers onto our platform, we’re creating a connected experience that streamlines workflows, reduces friction and costs, and ultimately drives better outcomes for members and our partners." Moving forward, the 400 payers and employers served by UCM will transition to Fabric’s expanded technology and clinical network, gaining access to enhanced omnichannel patient experiences that improve efficiency before, during, and after virtual care. Through Fabric’s nationwide provider network, patients can receive a treatment plan for most common medical conditions in just five minutes or connect with a behavioral health provider within three days.

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Flex has closed a $60 million Series B equity round led by Portage, bringing total equity raised to $105 million. In the last year, the company has quadrupled revenue and tripled its payments volume to $3 billion as it scales its all-in-one business and personal finance platform for high-net-worth middle-market business owners. Running a profitable middle-market business has become one of the most complex financial jobs in America, with owners often juggling more than ten disconnected systems to manage their money. Flex was created to give these high net worth owners a single place to run both their business and personal finances. This latest $60 Million equity round, followed by its $200 Million debt and $25 Million equity raise announced earlier this year, builds on a period of rapid hypergrowth. In just 12 months, Flex has grown revenue fourfold and increased annualized total payments volume from $1 billion to $3 billion across a suite of products, positioning Flex as one of the fastest-growing fintech companies at scale with best-in-class capital efficiency.

Flex is building the category-defining company solving this gap for high net worth business owners with a five-pillar strategy built around private credit, a business finance stack, a personal finance stack, payment solutions, and an ERP built for middle market businesses. These customers now use an average of four or more Flex products. Flex’s Business Credit Card, which provides 60-day float on every transaction, has been a major driver of adoption, acting as the wedge into deeper financial operations. Once owners experience the benefits of the Flex Credit Card, they often go on to adopt Flex’s banking, payments, working capital, and expense management tools to replace fragmented legacy systems. This integrated model has allowed Flex to scale with high efficiency and has created a strong foundation for its expansion into personal finance.

Launched in 2023, Flex a Flexbase Technologies brand is the AI Native “Private Bank” for high net worth business owners in the middle market. Flex is building the category-defining company solving this gap for high net worth business owners with a five-pillar strategy built around private credit, a business finance stack, a personal finance stack, payment solutions, and an ERP built for middle market businesses. Flex is the first platform that supports every step of their financial lives, from the moment they earn revenue to the moment they spend it personally.
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Across the United States, a new industrial age is taking shape. Trillions of dollars in infrastructure, from energy projects and advanced manufacturing to data centers and critical mineral facilities, must be built in the next decade. But large construction projects are slower and more expensive today than they were half a century ago. Unlimited Industries, a California-based company using AI to rethink how infrastructure gets built, has raised $12 million in seed funding to change that. The round was co-led by Andreessen Horowitz and CIV, with participation from leading industry investors. The capital will accelerate Unlimited’s expansion and further develop its proprietary AI platform – one designed to make large-scale engineering and construction faster, cheaper, and more ambitious.

Unlike traditional construction firms or standard software companies, Unlimited is an AI-native construction company that both designs and builds. Its proprietary platform can generate and evaluate hundreds of thousands of design configurations in parallel, automatically identifying optimal layouts for cost, safety, and performance before construction begins. By integrating AI-driven design with its own vertically integrated engineering and construction teams, Unlimited eliminates the costly handoffs and misaligned incentives that have defined the industry for decades.

In a statement Alex Modon, Co-Founder and CEO of Unlimited Industries said, “Advances in AI mean we can finally build the physical world the way we build software.” “The traditional construction model is slow, brittle, and fundamentally misaligned. Our approach replaces static design choices with a dynamic, data-driven process that learns from every project. The result is faster, cheaper, and more successful projects.”

Unlimited is an AI-native construction company headquartered in San Francisco. Today, the company designs and builds across energy infrastructure, data centers, critical minerals, and advanced manufacturing, helping developers build with greater speed, ambition, and efficiency. Their mission is to build a future of radical physical abundance by automating construction end-to-end. The company was founded in 2025 by serial founders Alex Modon, Jordan Stern, and Tara Viswanathan.
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